Name : Anti-CHRNA7 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN7170131349
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | CHRNA7 |
| Specificity | This antibody reacts specifically with CHRNA7 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human CHRNA7 |
| Gene ID | 1139 |
| Swiss Prot | P36544 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | The channel is blocked by alpha-bungarotoxin, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane, After binding acetylcholine |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | CHRNA7 Polyclonal Antibody |
| Other name | Anti-CHRNA7 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | CHRNA7 |
| Short name | Anti-CHRNA7 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, a 7 (neuronal) (polyclonal), nicotinic, antibody to-cholinergic receptor |
| Alternative technique | polyclonals |
| Alternative to gene target | CHRNA7 and IDBG-5070 and ENSG00000175344 and 1139, CHRNA7 and IDBG-630821 and ENSBTAG00000015775 and 282178, CHRNA7-2 and NACHRA7, Cell surfaces, Chrna7 and IDBG-190675 and ENSMUSG00000030525 and 11441, alpha 7 (neuronal), nicotinic, protein homodimerization activity, this GO :0000187 and activation of MAPK activity and biological process this GO :0001540 and beta-amyloid binding and molecular function this GO :0001666 and response to hypoxia and biological process this GO :0004889 and acetylcholine-activated cation-selective channel activity and molecular function this GO :0005230 and extracellular ligand-gated ion channel activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005892 and acetylcholine-gated channel complex and cellular component this GO :0006810 and transport and biological process this GO :0006811 and ion transport and biological process this GO :0006816 and calcium ion transport and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0007165 and signal transduction and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007613 and memory and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0015464 and acetylcholine receptor activity and molecular function this GO :0015643 and toxic substance binding and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0017081 and chloride channel regulator activity and molecular function this GO :0022848 and acetylcholine-gated cation channel activity and molecular function this GO :0030054 and cell junction and cellular component this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0035094 and response to nicotine and biological process this GO :0042166 and acetylcholine binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0045211 and postsynaptic membrane and cellular component this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0050890 and cognition and biological process, this GO :0001540: beta-amyloid binding, this GO :0001540: beta-amyloid binding and also this GO :0004889: acetylcholine-activated cation-selective channel activity and also this GO :0005230: extracellular ligand-gated ion channel activity and also this GO :0015464: acetylcholine receptor activity and also this GO :0015643: toxic substance binding and also this GO :0017081: chloride channel regulator activity and also this GO :0022848: acetylcholine-gated cation channel activity and also this GO :0042166: acetylcholine binding and also this GO :0042803: protein homodimerization activity, this GO :0004889: acetylcholine-activated cation-selective channel activity, this GO :0005230: extracellular ligand-gated ion channel activity, this GO :0015464: acetylcholine receptor activity, this GO :0015643: toxic substance binding, this GO :0017081: chloride channel regulator activity, this GO :0022848: acetylcholine-gated cation channel activity, this GO :0042166: acetylcholine binding, this GO :0042803: protein homodimerization activity, 89832, cholinergic receptor |
| Identity | 1960 |
| Gene | CHRNA7 |
| Long gene name | cholinergic receptor nicotinic alpha 7 subunit |
| Synonyms gene name | alpha 7 (neuronal) cholinergic receptor, alpha polypeptide 7 cholinergic receptor, cholinergic receptor, nicotinic, nicotinic, nicotinic alpha 7 |
| Synonyms name | acetylcholine receptor, alpha 7 (neuronal) , nicotinic |
| Locus | 15q13, 3 |
| Discovery year | 1993-05-25 |
| GenBank acession | Z23141 |
| Entrez gene record | 1139 |
| Pubmed identfication | 8188270 |
| Classification | Cholinergic receptors nicotinic subunits |
| Havana BLAST/BLAT | OTTHUMG00000129285 |