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Anti-Chromogranin C/Sg II (Polyclonal), ALEXA Fluor 594

Anti-Chromogranin C/Sg II (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideChromogranin C/Sg II
SpecificityThis antibody reacts specifically with Chromogranin C/Sg II
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Chromogranin C/Sg II
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Family members include chromogranin A (Chr-A), High levels of Chr-A expression are characteristic of neuroendocrine tumors, In neuroendocrine cells the level Sg II has been shown to increase four-fold in response to histamine, In the anterior lobe of the rat pituitary gland, Pancreastatin exists as two forms, Pancreastatin is a peptide derived from Chr-A which inhibits insulin secretion, Sg III and carboxypeptidase E (CPE) bind specifically to cholesterol-rich secretory granule (SG) membranes, Sg III is an acidic secretory protein expressed in neuronal and endocrine cells, Sg III is present in mammotropes and thyrotropes, also known as secretogranin I, and secretogranin III (Sg III or SCG3), chromogranin B (Chr-B), chromogranin C (also known as secretogranin II or Sg II), exocrine pancreatic secretion and gastric acid secretion, moderately in gonadotropes and corticotropes, neuroendocrine and neuronal tissue, the major form is expressed in stomach and colon extracts, though not in somatotropes, while levels of Chr-A and Chr-B showed little or no increase, Chromogranins (secretogranins) are acidic glycoproteins that localize within secretory granules of endocrine
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Chromogranin-C, MEN1, SCG2, SCG2_HUMAN, SN, Secretogranin II, Secretogranin-2, Secretoneurin, Secretoneurin included, SgII, CHGC
Also known asChromogranin C/Sg II Polyclonal Antibody
Other nameAnti-Chromogranin C/Sg II Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetChromogranin C/Sg II
Short nameAnti-Chromogranin C/Sg II (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Chromogranin C/Sg II (polyclonal)
Alternative techniquepolyclonals

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