Name : Anti-Chromogranin C/Sg II (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6311133097
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Chromogranin C/Sg II |
| Specificity | This antibody reacts specifically with Chromogranin C/Sg II |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human Chromogranin C/Sg II |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Family members include chromogranin A (Chr-A), High levels of Chr-A expression are characteristic of neuroendocrine tumors, In neuroendocrine cells the level Sg II has been shown to increase four-fold in response to histamine, In the anterior lobe of the rat pituitary gland, Pancreastatin exists as two forms, Pancreastatin is a peptide derived from Chr-A which inhibits insulin secretion, Sg III and carboxypeptidase E (CPE) bind specifically to cholesterol-rich secretory granule (SG) membranes, Sg III is an acidic secretory protein expressed in neuronal and endocrine cells, Sg III is present in mammotropes and thyrotropes, also known as secretogranin I, and secretogranin III (Sg III or SCG3), chromogranin B (Chr-B), chromogranin C (also known as secretogranin II or Sg II), exocrine pancreatic secretion and gastric acid secretion, moderately in gonadotropes and corticotropes, neuroendocrine and neuronal tissue, the major form is expressed in stomach and colon extracts, though not in somatotropes, while levels of Chr-A and Chr-B showed little or no increase, Chromogranins (secretogranins) are acidic glycoproteins that localize within secretory granules of endocrine |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | Chromogranin-C, MEN1, SCG2, SCG2_HUMAN, SN, Secretogranin II, Secretogranin-2, Secretoneurin, Secretoneurin included, SgII, CHGC |
| Also known as | Chromogranin C/Sg II Polyclonal Antibody |
| Other name | Anti-Chromogranin C/Sg II Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | Chromogranin C/Sg II |
| Short name | Anti-Chromogranin C/Sg II (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Chromogranin C/Sg II (polyclonal) |
| Alternative technique | polyclonals |