Name : Anti-CK12 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6594112970
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | CK12 |
| Specificity | This antibody reacts specifically with CK12 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human CK12/Cytokeratin 12 |
| Gene ID | 3859 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Cytokeratin 12 encodes the type I intermediate filament chain keratin 12, Defects in KRT12 are a cause of juvenile epithelial corneal dystrophy of Meesmann (MCD), Defects in KRT3 and KRT12 are a cause of Meesmann corneal dystrophy (MCD), Keratin 3 is specifically expressed in the corneal epithelium with family member KRT12, Symptoms occur in adulthood and include rupture of the corneal microcysts that may lead to photophobia, an autosomal dominant disease that causes fragility of the anterior corneal epithelium, contact lens intolerance and intermittent diminution of visual acuity, expressed in corneal epithelia, Cytokeratin 12 is a member of the intermediate filament family of proteins and is a heterotetramer of two type I and two type II keratins |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | CK 12, CK 3, CK12, CK3, Cytokeratin 12, Cytokeratin 3, K12, K1C12_HUMAN, K3, KRT12, KRT3, Keratin, Keratin, Keratin 12, Keratin 3, keratin 12 Meesmann corneal dystrophy, type I cytoskeletal 12, type II cytoskeletal 3, 65 kDa cytokeratin |
| Also known as | CK12 Polyclonal Antibody |
| Other name | Anti-CK12 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | CK12 |
| Short name | Anti-CK12 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-CK12 (polyclonal) |
| Alternative technique | polyclonals |