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Anti-Claudin 1 (Polyclonal), ALEXA Fluor 594

Anti-Claudin 1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideClaudin 1
SpecificityThis antibody reacts specifically with Claudin 1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from mouse Claudin 1
Gene ID12737
Swiss ProtO88551
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin, Often, Required for normal water homeostasis and to prevent excessive water loss through the skin, While some claudin family members play essential roles in the formation of impermeable barriers, and this determines the overall permeability, others mediate the permeability to ions and small molecules, probably via an indirect effect on the expression levels of other proteins, several claudin family members are coexpressed and interact with each other, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions, Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms SEMP1 ILVASC
Also known asClaudin 1 Polyclonal Antibody
Other nameAnti-Claudin 1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetClaudin 1
Short nameAnti-Claudin 1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Claudin 1 (polyclonal)
Alternative techniquepolyclonals
Identity 2032
Gene CLDN1
Long gene name claudin 1
Synonyms name senescence-associated epithelial membrane protein 1
Locus 3q28
Discovery year 1998-11-19
GenBank acession AF101051
Entrez gene record 9076
Pubmed identfication 10828592 9892664
RefSeq identity NM_021101
Classification Claudins
Havana BLAST/BLAT OTTHUMG00000156214

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