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Anti-Claudin 12 (Polyclonal), ALEXA Fluor 594

Anti-Claudin 12 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideClaudin 12
SpecificityThis antibody reacts specifically with Claudin 12
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human Claudin 12
Gene ID9069
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Ammonia can alter brain capillary endothelial cell gene expression and transporter function, Claudin-12, Claudin-12 is upregulated in enterocytes through vitamin D receptors which strongly suggest that claudin-12 forms paracellular Ca(2+) channels in intestinal epithelia and may be critical for vitamin D-dependent calcium homeostasis, Claudin-12 localizes to cell junctions and may be involved in tight junction integrity by regulating hyperammonemia, also known as CLDN12, and colon, duodenum, ileum, is a 244 amino acid multi-pass membrane protein that is expressed in the brain, jejunum, The claudin superfamily consists of many structurally related proteins that are important structural and functional components of tight junctions
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asClaudin 12 Polyclonal Antibody
Other nameAnti-Claudin 12 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetClaudin 12
Short nameAnti-Claudin 12 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Claudin 12 (polyclonal)
Alternative techniquepolyclonals
Identity 2034
Gene CLDN12
Long gene name claudin 12
Locus 7q21, 13
Discovery year 1998-12-11
GenBank acession AJ250713
Entrez gene record 9069
RefSeq identity NM_012129
Classification Claudins
Havana BLAST/BLAT OTTHUMG00000156612

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