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Anti-Claudin 16 (Polyclonal), ALEXA Fluor 594

Anti-Claudin 16 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideClaudin 16
SpecificityThis antibody reacts specifically with Claudin 16
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human Claudin 16
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Mutations in PCLN-1 cause renal magnesium wasting, PCLN-1 contains four transmembrane domains and intracellular amino and carboxy termini, PCLN-1 forms an intercellular pore and controls the resorption of magnesium and calcium in the thick ascending limb of Henle (TAL), The human gene PCLN-1 (paracellin-1) is related to the claudin family of integral membrane proteins, They form close connections to eliminate the extracellular space and regulate the flow of solutes between cells, and is detected only at the tight junctions of kidney tissue, characteristic of the other claudin family members, renal hypomagnesemia with hypercalciuria and nephrocalcinosis, which localize to tight junctions, which may contribute to a rare autosomal recessive disease, Tight junctions mediate the regulation of the paracellular pathway between epithelial and endothelial cells
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PCLN1 HOMG3
Also known asClaudin 16 Polyclonal Antibody
Other nameAnti-Claudin 16 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetClaudin 16
Short nameAnti-Claudin 16 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Claudin 16 (polyclonal)
Alternative techniquepolyclonals
Identity 2037
Gene CLDN16
Long gene name claudin 16
Synonyms name paracellin-1 hypomagnesemia 3, with hypercalciuria and nephrocalcinosis
Locus 3q28
Discovery year 2000-01-07
GenBank acession AF152101
Entrez gene record 10686
Pubmed identfication 10390358
RefSeq identity NM_006580
Classification Claudins
Havana BLAST/BLAT OTTHUMG00000156215

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