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Anti-Claudin 23 (Polyclonal), ALEXA Fluor 594

Anti-Claudin 23 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideClaudin 23
SpecificityThis antibody reacts specifically with Claudin 23
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human Claudin 23
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Claudin-23, Expressed in stomach and placenta, Human claudin-23 shares 80% sequence similarity with its mouse counterpart, Overexpression of claudin-23 is associated with colon tumors, also known as CLDN23 or CLDNL, as well as in germinal center B-cells, claudin-23 is thought to exhibit calcium-dependent cell-adhesion activity through which it plays an essential role in tight junction-specific obliteration of the intercellular space, implicating claudin-23 as a possible metastasis factor, is a 292 amino acid multi-pass membrane protein that localizes to cell junctions and belongs to the claudin family, suggesting a conserved role between species, The claudin superfamily consists of structurally related proteins that are important structural and functional components of tight junctions
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CLDNL
Also known asClaudin 23 Polyclonal Antibody
Other nameAnti-Claudin 23 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetClaudin 23
Short nameAnti-Claudin 23 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Claudin 23 (polyclonal)
Alternative techniquepolyclonals
Identity 17591
Gene CLDN23
Long gene name claudin 23
Locus 8p23, 1
Discovery year 2004-06-14
GenBank acession AK123547
Entrez gene record 137075
Pubmed identfication 12736707
RefSeq identity NM_194284
Classification Claudins
Havana BLAST/BLAT OTTHUMG00000163674

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