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Anti-CLCA3 (Polyclonal), ALEXA Fluor 594

Anti-CLCA3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCLCA3
SpecificityThis antibody reacts specifically with CLCA3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from mouse CLCA3
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Rat (Rattus norvegicus), Mouse (Mus musculus)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CLCA1 is expressed as a precursor protein that is processed into two cell surface associated subunits and a group of proteins, CLCA1 is upregulated by interleukin-9 and regulates the expression of mucins, CLCA1 may provide a therapeutic target to control mucus overproduction in airway disease patients with cystic fibrosis, CLCA2 expression is downregulated in breast cancer, CLCA3 (known as Clca3 in mouse) is a structurally divergent member of the CLCA family that does not function as a channel protein, CLCA4 is a CLCA member that is expressed in human rectal mucosa, CLCA5 shows strong expression in eye and spleen, and CLCA6 is primarily expressed in intestine and stomach, display distinct tissue distribution patterns, therefore CLCA2 is thought to act as a tumor suppressor in normal cells, which includes the human homologs CLCA1 and CLCA2, The calcium-activated chloride channel (CLCA) protein family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asCLCA3 Polyclonal Antibody
Other nameAnti-CLCA3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCLCA3
Short nameAnti-CLCA3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CLCA3 (polyclonal)
Alternative techniquepolyclonals
Identity 2017
Gene CLCA3P
Long gene name chloride channel accessory 3, pseudogene
Synonyms gene CLCA3
Synonyms gene name calcium activated, chloride channel, family member 3 chloride channel regulator 3
Locus 1p22, 3
Discovery year 1998-10-02
GenBank acession AF043976
Entrez gene record 9629
Pubmed identfication 10095065
RefSeq identity NM_004921
Classification Chloride channel accessory
Havana BLAST/BLAT OTTHUMG00000010258

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