Anti-CLCNKB (Polyclonal), ALEXA Fluor 594

Anti-CLCNKB (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	CLCNKB
Specificity	This antibody reacts specifically with CLCNKB
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human CLCNKB
Gene ID	N/A
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	CLC-KA is a kidney-specific chloride channel that mediates transepithelial chloride transport in the thin ascending limb of the Henle loop in the inner medulla, CLC-KA plays a crucial role in urine concentration, CLC-KB mediates basolateral chloride ion efflux in the thick ascending limb and in more distal nephron segments, CLCs regulate excitability in muscle and nerve cells, Mutations in this gene cause type III Barterâ, Mutations in this gene may be associated with nephrogenic diabetes insipidus in those cases where mutations in the vasopressin V2 receptor and the AQP2 water channel are lacking, The gene encoding human CLC-KA maps to chromosome 1p36, The gene encoding human CLC-KB maps to chromosome 1p36, a critical component of all living cells, aid in organic solute transport, and maintain cellular volume, &euro, &trade, The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, s syndrome which is characterized by renal salt-wasting and low blood pressure
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	hClC-Kb
Also known as	CLCNKB Polyclonal Antibody
Other name	Anti-CLCNKB Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	CLCNKB
Short name	Anti-CLCNKB (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-CLCNKB (polyclonal)
Alternative technique	polyclonals
Identity	2027
Gene	CLCNKB
Long gene name	chloride voltage-gated channel Kb
Synonyms gene name	chloride channel Kb chloride channel, voltage-sensitive Kb
Locus	1p36, 13
Discovery year	1995-12-11
GenBank acession	AK098217
Entrez gene record	1188
RefSeq identity	NM_000085
Classification	Chloride voltage-gated channels
Havana BLAST/BLAT	OTTHUMG00000009530

Anti-CLCNKB (Polyclonal), ALEXA Fluor 594

Anti-CLCNKB (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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