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Anti-CLEC5A (Polyclonal), ALEXA Fluor 594

Anti-CLEC5A (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCLEC5A
SpecificityThis antibody reacts specifically with CLEC5A
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from mouse CLEC5A
Gene ID23845
Swiss ProtQ9R007
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation, Cell surface receptor that signals via TYROBP, Critical macrophage receptor for dengue virus serotypes 1-4, Regulates inflammatory responses, The binding of dengue virus to CLEC5A triggers signaling through phosphylation of TYROBP, this interaction does not result in viral entry but stimulates proinflammatory cytokine release, Functions as a positive regulator of osteoclastogenesis
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MDL-1
Also known asCLEC5A Polyclonal Antibody
Other nameAnti-CLEC5A Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCLEC5A
Short nameAnti-CLEC5A (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, member A (polyclonal), antibody to-C-classification lectin domain family 5
Alternative techniquepolyclonals
Alternative to gene target CLEC5A and IDBG-546985 and ENSG00000258227 and 23601, CLEC5A and IDBG-636542 and ENSBTAG00000020453 and 615201, CLECSF5 and MDL-1 and MDL1, Cell surfaces, Clec5a and IDBG-139294 and ENSMUSG00000029915 and 23845, carbohydrate binding, member A, this GO :0001618 and virus receptor activity and molecular function this GO :0002076 and osteoblast development and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006968 and cellular defense response and biological process this GO :0007165 and signal transduction and biological process this GO :0009615 and response to virus and biological process this GO :0009986 and cell surface and cellular component this GO :0016032 and viral process and biological process this GO :0030246 and carbohydrate binding and molecular function this GO :0033033 and negative regulation of myeloid cell apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0050715 and positive regulation of cytokine secretion and biological process, this GO :0001618: virus receptor activity, this GO :0001618: virus receptor activity and also this GO :0005515: protein binding and also this GO :0030246: carbohydrate binding, this GO :0005515: protein binding, this GO :0030246: carbohydrate binding, C-type lectin domain family 5
Identity 2054
Gene CLEC5A
Long gene name C-type lectin domain family 5 member A
Synonyms gene CLECSF5
Synonyms gene name C-type (calcium dependent, carbohydrate-recognition domain) lectin, member A , superfamily member 5 C-type lectin domain family 5
Locus 7q34
Discovery year 1999-10-19
Entrez gene record 23601
Pubmed identfication 10449773
RefSeq identity NM_013252
Classification C-type lectin domain family
Havana BLAST/BLAT OTTHUMG00000157173

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