Anti-CLN6 (Polyclonal), ALEXA Fluor 594

Anti-CLN6 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	CLN6
Specificity	This antibody reacts specifically with CLN6
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human CLN6
Gene ID	N/A
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	CLN6 is one of eight proteins, Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function, a 311 amino acid protein, a lysosomal storage disorder marked by progressive mental deterioration and blindness, causing the death of neurons, has seven predicted transmembrane domains and is conserved across vertebrates, including CLN1-8, part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, that are associated with NCL, CLN6
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	FLJ20561 HsT18960 nclf
Also known as	CLN6 Polyclonal Antibody
Other name	Anti-CLN6 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	CLN6
Short name	Anti-CLN6 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-CLN6 (polyclonal)
Alternative technique	polyclonals
Identity	2077
Gene	CLN6
Long gene name	ceroid-lipofuscinosis, late infantile, neuronal 6, variant
Locus	15q23
Discovery year	1996-10-11
GenBank acession	AK000568
Entrez gene record	54982
Pubmed identfication	9097964 11727201
RefSeq identity	NM_017882
Havana BLAST/BLAT	OTTHUMG00000133286
Locus Specific Databases	NCL Mutations LRG_832 , Neuronal Ceroid Lipofuscinoses

Anti-CLN6 (Polyclonal), ALEXA Fluor 594

Anti-CLN6 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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