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Anti-CLNS1A (Polyclonal), ALEXA Fluor 594

Anti-CLNS1A (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCLNS1A
SpecificityThis antibody reacts specifically with CLNS1A
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human CLNS1A/pICln
Gene ID1207
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information JBP1), PRMT5 binds the Sm proteins via their arginine- and glycine-rich (RG) domains, The gene encoding human pICln maps to chromosome 11q14, This process is mediated by the survival of motor neuron (SMN) protein, a complex comprised of the type II methyltransferase PRMT5 (also designated Jak-binding protein 1, and is enhanced by modification of specific arginine residues in the Sm proteins to symmetrical dimethylarginines (sDMAs), and may play a role as a swelling-activated anion channel or a channel regulator in addition to its function in the methylosome, and two novel factors, pICln, pICln also acts as an inhibitor of SnRNP assembly by preventing specific interactions between Sm proteins required for the formation of the Sm core, pICln is a highly conserved, sDMA modification of Sm proteins is catalyzed by the methylosome, ubiquitously expressed protein that localizes primarily to the cytoplasm, while pICln binds the Sm domains, 1, The formation of the spliceosome includes the assembly of Sm proteins in an ordered manner onto snRNAs
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms ICln
Also known asCLNS1A Polyclonal Antibody
Other nameAnti-CLNS1A Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCLNS1A
Short nameAnti-CLNS1A (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CLNS1A (polyclonal)
Alternative techniquepolyclonals
Identity 2080
Gene CLNS1A
Long gene name chloride nucleotide-sensitive channel 1A
Synonyms gene CLCI
Synonyms gene name 1A , chloride channel, nucleotide-sensitive
Synonyms name methylosome subunit pICln
Locus 11q14, 1
Discovery year 1997-10-16
GenBank acession U17899
Entrez gene record 1207
Pubmed identfication 7887970 8975725
RefSeq identity NM_001293
Havana BLAST/BLAT OTTHUMG00000165143

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