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Anti-CNOT4 (Polyclonal), ALEXA Fluor 594

Anti-CNOT4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCNOT4
SpecificityThis antibody reacts specifically with CNOT4
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human CNOT4
Gene ID4850
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CNOT4 (CCR4-NOT transcription complex subunit 4), CNOT4 binds E2 ubiquitin ligases, CNOT4 contains one C3H1-type zinc finger, CNOT4 functions as a UbcH5B-dependent ubiquitin-protein ligase (E3 ligase), The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome, There are eight isoforms of CNOT4 that are expressed as a result of alternative splicing events, Various subunits within the complex are involved in influencing nuclear hormone receptor activities, Via its RING domain, also known as CCR4-associated factor 4 and E3 ubiquitin-protein ligase CNOT4, is a 575 amino acid protein that is a subunit of the CCR4-NOT complex, multi-component complex known to be involved in transcription as well as mRNA degradation, one RING-type zinc finger and one RRM (RNA recognition motif) domain, The CCR4-NOT complex is an evolutionarily conserved
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CLONE243 NOT4H
Also known asCNOT4 Polyclonal Antibody
Other nameAnti-CNOT4 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCNOT4
Short nameAnti-CNOT4 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CNOT4 (polyclonal)
Alternative techniquepolyclonals
Identity 7880
Gene CNOT4
Long gene name CCR4-NOT transcription complex subunit 4
Synonyms gene NOT4
Synonyms gene name CCR4-NOT transcription complex, subunit 4
Locus 7q33
Discovery year 1996-07-19
GenBank acession AF180475
Entrez gene record 4850
Pubmed identfication 10637334
RefSeq identity NM_013316
Classification CCR4-NOT transcription complex RNA binding motif containing
Havana BLAST/BLAT OTTHUMG00000155568

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