Name : Anti-CNOT8 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6328081962
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | CNOT8 |
| Specificity | This antibody reacts specifically with CNOT8 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human CNOT8 |
| Gene ID | 9337 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | CNOT8 (CCR4-NOT transcription complex subunit 8), CNOT8 plays a role in transcriptional regulation for a diverse set of processes, Expressed ubiquitously, The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome, Various subunits within the complex are involved in influencing nuclear hormone receptor activities, also known as CALIF or POP2, is a 292 amino acid protein that localizes to both the nucleus and the cytoplasm and functions as part of the CCR-NOT complex, multi-component complex known to be involved in transcription as well as mRNA degradation, The CCR4-NOT complex is an evolutionarily conserved |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | CAF1 hCAF1 CALIF |
| Also known as | CNOT8 Polyclonal Antibody |
| Other name | Anti-CNOT8 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | CNOT8 |
| Short name | Anti-CNOT8 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-CNOT8 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 9207 |
| Gene | CNOT8 |
| Long gene name | CCR4-NOT transcription complex subunit 8 |
| Synonyms gene | POP2 |
| Synonyms gene name | CCR4-NOT transcription complex, subunit 8 |
| Synonyms name | PGK promoter directed over production |
| Locus | 5q33, 2 |
| Discovery year | 1998-09-25 |
| GenBank acession | AF053318 |
| Entrez gene record | 9337 |
| Pubmed identfication | 10036195 10637334 |
| RefSeq identity | NM_004779 |
| Classification | CCR4-NOT transcription complex |
| Havana BLAST/BLAT | OTTHUMG00000130192 |