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Anti-Complement fragment 3c, ALEXA Fluor 594

Anti-Complement fragment 3c, ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideComplement fragment 3c
SpecificityThis antibody reacts specifically with Complement fragment 3c
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsSecreted
Antigen SourceKLH conjugated synthetic peptide derived from human Complement C3c alpha' chain fragment 1
Gene ID718
Swiss ProtP01024
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Pig/Swine (Sus scrofa), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ARRB2-mediated internalization and recycling of C5AR2 (PubMed:837664, Acylation stimulating protein: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, After activation C3b can bind covalently, Appears to stimulate TG synthesis via activation of the PLC, C3-beta-c: Acts as a chemoattractant for neutrophils in chronic inflammation, C3a anaphylatoxin is a mediator of local inflammatory process, Derived from proteolytic degradation of complement C3, In chronic inflammation, It induces the contraction of smooth muscle, Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways, Ligand for C5AR2, MAPK and AKT signaling pathways, Promotes the phosphorylation, PubMed:1432298, PubMed:15833747, PubMed:16333141, PubMed:1961575), PubMed:29953, PubMed:959512, acts as a chemoattractant for neutrophils (By similarity), increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes, regulating fat storage and playing a role in postprandial TG clearance, to cell surface carbohydrates or immune aggregates, via its reactive thioester, C3 plays a central role in the activation of the complement system
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms AHUS5, ARMD9, C3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3a, C3b, CPAMD1, Complement C3, HEL-S-62p, ASP
Also known asComplement fragment 3c Antibody
Other nameAnti-Complement fragment 3c
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetComplement 3c
Short name Fluor 594, Anti-Complement 3c
Isotype Complement fragments, Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small, IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion, bp DNA fragments are common, coli expressed, single chain variable fragments can be E, Antibody fragments and scFv fragments
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Complement fragment 3c

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