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Anti-Connexin 43 (Polyclonal), ALEXA Fluor 594

Anti-Connexin 43 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideConnexin 43
SpecificityThis antibody reacts specifically with Connexin 43
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human Connexin-43
Gene ID2697
Swiss ProtP17302
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Dog, Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A gap junction consists of a cluster of closely packed pairs of transmembrane channels, May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph, Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity), Gap junction protein that acts as a regulator of bladder capacity
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CX43 ODD ODOD SDTY3
Also known asConnexin 43 Polyclonal Antibody
Other nameAnti-Connexin 43 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetConnexin 43
Short nameAnti-Connexin 43 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Connexin 43 (polyclonal)
Alternative techniquepolyclonals
Identity 4274
Gene GJA1
Long gene name gap junction protein alpha 1
Synonyms gene ODDD GJAL
Synonyms gene name 43kDa , 43kDa (connexin 43) gap junction protein, alpha 1, alpha 1, alpha-like gap junction protein, gap junction protein
Synonyms name oculodentodigital dysplasia (syndactyly type III) connexin 43
Locus 6q22, 31
Discovery year 1990-08-03
GenBank acession BC026329
Entrez gene record 2697
Pubmed identfication 10331943 1646158
RefSeq identity NM_000165
Classification Gap junction proteins
Havana BLAST/BLAT OTTHUMG00000015479
Locus Specific Databases Hereditary Hearing Loss Homepage

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