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Anti-CPB2 (Polyclonal), ALEXA Fluor 594

Anti-CPB2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCPB2
SpecificityThis antibody reacts specifically with CPB2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human CPB2
Gene ID1361
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A deficiency might contribute to the severity of bleeding disorders in hemophilias A and B, Activated carboxypeptidase B2 removes C-terminal lysine residues from fibrin, Being activated by thrombin-thrombomodulin complex during blood coagulation, Elevated concentration in blood is considered as a risk factor for venous thrombosis, High plasma levels were found in patients with stable angina pectoris and angiographically verified coronary artery disease, It circulates in plasma as a zymogen with molecular weight of 55 kDa (401 amino acid residues, The concentration in plasma of healthy people is 5-10 ug/ml, This prevents plasminogen from activation into plasmin and retards the lysis of a fibrin clot, and decreased levels are found in chronic liver disease, it exerts carboxypeptidase activity, pI 5, which is necessary for plasminogen binding to fibrin, 0), This protein belongs to a family of Zn-containing metallocarboxypeptidases specific to C-terminal lysine and arginine residues
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CPU PCPB TAFI
Also known asCPB2 Polyclonal Antibody
Other nameAnti-CPB2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCPB2
Short nameAnti-CPB2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CPB2 (polyclonal)
Alternative techniquepolyclonals
Identity 2300
Gene CPB2
Long gene name carboxypeptidase B2
Synonyms gene name carboxypeptidase B2 (plasma, carboxypeptidase U) carboxypeptidase B2 (plasma)
Synonyms name thrombin-activatable fibrinolysis inhibitor carboxypeptidase U plasma carboxypeptidase B carboxypeptidase R
Locus 13q14, 13
Discovery year 1992-04-10
GenBank acession M75106
Entrez gene record 1361
Pubmed identfication 1939207 1427879
RefSeq identity NM_001872
Classification Carboxypeptidases
Havana BLAST/BLAT OTTHUMG00000016867

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