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Anti-CPN2 (Polyclonal), ALEXA Fluor 594

Anti-CPN2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCPN2
SpecificityThis antibody reacts specifically with CPN2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human CPN2
Gene ID1370
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Because of the highly conserved active sites and the possible redundant functions of carboxypeptidases, By removing only one amino acid, CPN has the ability to change peptide activity and receptor binding, CPN is a member of a larger family of carboxypeptidases, CPN2, It consists of 2 identical 83 kDa regulatory subunits (CPN2) and 2 identical 50 kDa catalytic subunits (CPN1), It is a 280 kDa tetrameric glycoprotein that is synthesized by the liver and secreted into the plasma, Under some circumstances it may be an allosteric modifier of the catalytic subunit, and cleaves carboxy-terminal arginines and lysines from peptides found in the bloodstream such as complement anaphylatoxins, and creatine kinase MM (CK-MM), binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation, it has been difficult to elucidate the role of CPN in disease processes, kinins, many of which also cleave arginine and lysine, the 83 kDa subunit, CPN2 is a zinc metalloprotease
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CPN2
Also known asCPN2 Polyclonal Antibody
Other nameAnti-CPN2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCPN2
Short nameAnti-CPN2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CPN2 (polyclonal)
Alternative techniquepolyclonals
Identity 2315
Gene CPNE2
Long gene name copine 2
Synonyms gene name copine II
Locus 16q13
Discovery year 1999-02-09
Entrez gene record 221184
Pubmed identfication 9430674
RefSeq identity NM_152727
Classification Copines
Havana BLAST/BLAT OTTHUMG00000133471

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