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Anti-CRMP3 (Polyclonal), ALEXA Fluor 594

Anti-CRMP3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCRMP3
SpecificityThis antibody reacts specifically with CRMP3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human CRMP3
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum, CRMP-4 (DRP-3) and CRMP-5 (DRP-5), CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A, However, In the adult brain, It is cleaved by Calpain to produce a p54 N-terminal fragment, This cleavage product translocates to the nucleus and induces neuronal death in response to excitotoxicity and cerebral ischemia, including CRMP-1 (DRP-1), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin, the expression of CRMPs is dramatically downregulated, they remain expressed in structures that retain their capacity for differentiation and plasticity, Collapsin response mediator proteins (CRMPs)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CRMP 3, CRMP-3, CRMP3, DPYL4_HUMAN, DPYSL4, DRP 4, DRP-4, DRP4, Dihydropyrimidinase like 4, Dihydropyrimidinase related protein 4, Dihydropyrimidinase-related protein 4, ULIP 4, ULIP-4, ULIP4, UNC33 like phosphoprotein 4, UNC33-like phosphoprotein 4, Collapsin response mediator protein 3
Also known asCRMP3 Polyclonal Antibody
Other nameAnti-CRMP3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCRMP3
Short nameAnti-CRMP3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CRMP3 (polyclonal)
Alternative techniquepolyclonals

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