Name : Anti-CRMP3 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6138012451
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | CRMP3 |
| Specificity | This antibody reacts specifically with CRMP3 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human CRMP3 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum, CRMP-4 (DRP-3) and CRMP-5 (DRP-5), CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A, However, In the adult brain, It is cleaved by Calpain to produce a p54 N-terminal fragment, This cleavage product translocates to the nucleus and induces neuronal death in response to excitotoxicity and cerebral ischemia, including CRMP-1 (DRP-1), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin, the expression of CRMPs is dramatically downregulated, they remain expressed in structures that retain their capacity for differentiation and plasticity, Collapsin response mediator proteins (CRMPs) |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | CRMP 3, CRMP-3, CRMP3, DPYL4_HUMAN, DPYSL4, DRP 4, DRP-4, DRP4, Dihydropyrimidinase like 4, Dihydropyrimidinase related protein 4, Dihydropyrimidinase-related protein 4, ULIP 4, ULIP-4, ULIP4, UNC33 like phosphoprotein 4, UNC33-like phosphoprotein 4, Collapsin response mediator protein 3 |
| Also known as | CRMP3 Polyclonal Antibody |
| Other name | Anti-CRMP3 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | CRMP3 |
| Short name | Anti-CRMP3 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-CRMP3 (polyclonal) |
| Alternative technique | polyclonals |