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Anti-CSN7b (Polyclonal), ALEXA Fluor 594

Anti-CSN7b (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCSN7b
SpecificityThis antibody reacts specifically with CSN7b
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human CSN7b
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information COPS7a) or CSN7b (COP7b) and CSN8 (COP8), CSN2 (COPS2), CSN3, CSN3 (COPS3), CSN4, CSN4 (COPS4), CSN5, CSN5 (COPS5), CSN6, CSN6 (COP6), CSN7 is phosphorylated by CK2 and is composed of two subunits, CSN7a (COPS7, CSN7a contains a PCI (Proteasome CSN9 initiation factor 3) region, CSN7b contains only a PCI region and is predicted to interact with INT6, CSN8, I&, It is also involved in the phosphorylation of p53, The CSN complex acts as a regulator for the ubiquitin conjugation pathway by mediating the deneddylation of the SCF-type E3 ligase complexes, The complex is made up of several widely expressed proteins: CSN1 (COPS1), a and b, and GPS1, and IRF-8, and c-Jun protects and promotes degradation by the Ubl system, as well as CSN-dependent phosphorylation of p53, as well as a coiled-coil region and is predicted to interact with CSN2, c-Jun, which leads to a decrease in ubiquitin ligase activity of SCF-complexes, #730, B&, The COP9 signalosome (CSN) complex is involved in several different developmental and cellular processes, aring
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CSN7B
Also known asCSN7b Polyclonal Antibody
Other nameAnti-CSN7b Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCSN7b
Short nameAnti-CSN7b (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CSN7b (polyclonal)
Alternative techniquepolyclonals
Identity 16760
Gene COPS7B
Long gene name COP9 signalosome subunit 7B
Synonyms gene name Arabidopsis, COP9 (constitutive photomorphogenic, homolog) subunit 7B COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis)
Locus 2q37, 1
Discovery year 2001-10-03
GenBank acession AK022674
Entrez gene record 64708
Pubmed identfication 9707402
RefSeq identity NM_022730
Classification COP9 signalosome
Havana BLAST/BLAT OTTHUMG00000133228

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