Name : Anti-CT27 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN9403602515
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | CT27 |
| Specificity | This antibody reacts specifically with CT27 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human BORIS/CT27 |
| Gene ID | 140690 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, In association with DNMT1 and DNMT3B, Plays a key role in gene imprinting in male germline, Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters, Seems to act as tumor suppressor, This probably leads to recruit de novo DNA methyltransferases at these sites (By similarity), by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR), involved in activation of BAG1 gene expression by binding to its promoter, leading to methylate histone H4 'Arg-3' to form H4R3sme2, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers, Testis-specific DNA binding protein responsible for insulator function |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | dJ579F20, 2 BORIS CT27 |
| Also known as | CT27 Polyclonal Antibody |
| Other name | Anti-CT27 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | CT27 |
| Short name | Anti-CT27 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-CT27 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 16234 |
| Gene | CTCFL |
| Long gene name | CCCTC-binding factor like |
| Synonyms gene name | CCCTC-binding factor (zinc finger protein)-like |
| Synonyms name | cancer/testis antigen 27 transcriptional repressor CTCFL |
| Locus | 20q13, 31 |
| Discovery year | 2001-07-17 |
| Entrez gene record | 140690 |
| RefSeq identity | NM_080618 |
| Classification | Zinc fingers C2H2-type |
| Havana BLAST/BLAT | OTTHUMG00000032829 |