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Anti-Cullin 5 (Polyclonal), ALEXA Fluor 594

Anti-Cullin 5 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCullin 5
SpecificityThis antibody reacts specifically with Cullin 5
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Cullin 5
Gene ID1729
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme, ECS(SOCS1) seems to direct ubiquitination of JAk2, May form a cell surface vasopressin receptor, Seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein, The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms VACM-1
Also known asCullin 5 Polyclonal Antibody
Other nameAnti-Cullin 5 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCullin 5
Short nameAnti-Cullin 5 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Cullin 5 (polyclonal)
Alternative techniquepolyclonals
Identity 2556
Gene CUL5
Long gene name cullin 5
Locus 11q22, 3
Discovery year 1998-12-23
GenBank acession X81882
Entrez gene record 8065
Pubmed identfication 8681378 9037604
Classification Cullins
Havana BLAST/BLAT OTTHUMG00000166369

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