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Anti-Cullin 7 (Polyclonal), ALEXA Fluor 594

Anti-Cullin 7 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCullin 7
SpecificityThis antibody reacts specifically with Cullin 7
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Cullin 7
Gene ID9820
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information An autosomal recessive disorder characterized by severe pre- and postnatal growth retardation, In vitro, Probably plays a role in the degradation of proteins involved in endothelial proliferation and/or differentiation (By similarity), Seems not to promote polyubiquitination and proteasomal degradation of TP53, Skeletal changes include long slender tubular bones and tall vertebral bodies, and normal intelligence and endocrine function, complexes of CUL7 with either CUL9 or FBXW8 or TP53 contain E3 ubiquitin-protein ligase activity, facial dysmorphism, large head circumference, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, Component of a probable SCF-like E3 ubiquitin-protein ligase complex, Involvement in disease: Defects in CUL7 are the cause of 3M syndrome type 1 (3M1)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms dJ20C7, 5
Also known asCullin 7 Polyclonal Antibody
Other nameAnti-Cullin 7 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCullin 7
Short nameAnti-Cullin 7 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Cullin 7 (polyclonal)
Alternative techniquepolyclonals
Identity 21024
Gene CUL7
Long gene name cullin 7
Synonyms gene KIAA0076
Synonyms gene name KIAA0076
Locus 6p21, 1
Discovery year 2003-11-21
GenBank acession BC033647
Entrez gene record 9820
Pubmed identfication 12481031 12904573
RefSeq identity NM_014780
Classification Cullins
Havana BLAST/BLAT OTTHUMG00000014718

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