Name : Anti-Cyclin D3 (Thr283) (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :516
SKU : GEN7871617407
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Cyclin D3 Thr283 |
| Specificity | This antibody reacts specifically with Cyclin D3 (Thr283) |
| Modification | Phosphorylation |
| Modification site | Thr283 |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic phosphopeptide derived from human Cyclin D3 around the phosphorylation site of Thr283 |
| Gene ID | 896 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Cyclins function as regulators of CDK kinases, Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event, Oct 2008], Several transcript variants encoding different isoforms have been found for this gene, The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation, This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb, [provided by RefSeq, whose activtiy is required for cell cycle G1/S transition, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle, The protein encoded by this gene belongs to the highly conserved cyclin family |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | CCND 3, CCND3_HUMAN, Ccnd3, Cyclin D3 phospho Thr283, CyclinD3, D3 type cyclin, G1 S specic cyclin D3, G1/S specic cyclin D3, G1/S-specic cyclin-D3, p-Cyclin D3 T283, p-Cyclin D3 Thr283, p-Cyclin D3 phospho T283, Cyclin D3 phospho T283 |
| Also known as | Cyclin D3 (Thr283) Polyclonal Antibody |
| Other name | Anti-Cyclin D3 (Thr283) Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | Cyclin D3 (Thr283) |
| Short name | Anti-Cyclin D3 (Thr283) (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Cyclin D3 (Thr283) (polyclonal) |
| Alternative technique | polyclonals |