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Anti-CYP8A1/PTGIS (Polyclonal), ALEXA Fluor 594

Anti-CYP8A1/PTGIS (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCYP8A1/PTGIS
SpecificityThis antibody reacts specifically with CYP8A1/PTGIS
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human CYP8A1/PTGIS
Gene ID5740
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, However, The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation, and atherosclerosis, steroids and other lipids, stroke, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity, This gene encodes a member of the cytochrome P450 superfamily of enzymes
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PGIS CYP8A1
Also known asCYP8A1/PTGIS Polyclonal Antibody
Other nameAnti-CYP8A1/PTGIS Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCYP8A1/PTGIS
Short nameAnti-CYP8A1/PTGIS (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CYP8A1/prostaglandin I2 (prostacyclin) synthase (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target CYP8 and CYP8A1 and PGIS and PTGI, PTGIS and IDBG-643178 and ENSBTAG00000017537 and 101910090, PTGIS and IDBG-80513 and ENSG00000124212 and 5740, Ptgis and IDBG-213024 and ENSMUSG00000017969 and 19223, acting on paired donors, acting on paired donors, acting on paired donors, nuclei, oxidoreductase activity, this GO :0001516 and prostaglandin biosynthetic process and biological process this GO :0004497 and monooxygenase activity and molecular function this GO :0005506 and iron ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005901 and caveola and cellular component this GO :0006690 and icosanoid metabolic process and biological process this GO :0006805 and xenobiotic metabolic process and biological process this GO :0008116 and prostaglandin-I synthase activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016705 and oxidoreductase activity, this GO :0004497: monooxygenase activity, this GO :0004497: monooxygenase activity and also this GO :0005506: iron ion binding and also this GO :0005515: protein binding and also this GO :0008116: prostaglandin-I synthase activity and also this GO :0016705: oxidoreductase activity, this GO :0005506: iron ion binding, this GO :0005515: protein binding, this GO :0008116: prostaglandin-I synthase activity, this GO :0016705: oxidoreductase activity, this GO :0020037: heme binding, with incorporation or reduction of molecular oxygen, with incorporation or reduction of molecular oxygen and also this GO :0020037: heme binding, with incorporation or reduction of molecular oxygen and molecular function this GO :0019369 and arachidonic acid metabolic process and biological process this GO :0019371 and cyclooxygenase pathway and biological process this GO :0020037 and heme binding and molecular function this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0035360 and positive regulation of peroxisome proliferator activated receptor signaling pathway and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045019 and negative regulation of nitric oxide biosynthetic process and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071354 and cellular response to interleukin-6 and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :1900119 and positive regulation of execution phase of apoptosis and biological process, 282021, prostaglandin I2 (prostacyclin) synthase
Identity 9603
Gene PTGIS
Long gene name prostaglandin I2 synthase
Synonyms gene name prostaglandin I2 (prostacyclin) synthase
Synonyms name cytochrome P450, family 8, polypeptide 1 prostacyclin synthase , subfamily A
Locus 20q13, 13
Discovery year 1994-07-28
Entrez gene record 5740
Pubmed identfication 8812456
Classification Cytochrome P450 family 8
Havana BLAST/BLAT OTTHUMG00000033077
Locus Specific Databases Human Cytochrome P450 (CYP) Allele Nomenclature Committee

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