Anti-Cyr61 (Polyclonal), ALEXA Fluor 594

Anti-Cyr61 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	Cyr61
Specificity	This antibody reacts specifically with Cyr61
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Secreted
Antigen Source	KLH conjugated synthetic peptide derived from human Cyr61
Gene ID	3491
Swiss Prot	O00622
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Appears to play a role in wound healing by up-regulating, CYR61-mediated gene regulation is dependent on heparin-binding, Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1, MMP1, MMP3, PAI-1 and integrins alpha-3 and alpha-5, Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, TIMP1, VEGA-C, angiogenesis and cell adhesion, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3, chemotaxis, in skin fibroblasts, inflammation and matrix remodeling including VEGA-A, the expression of a number of genes involved in angiogenesis, uPA, Promotes cell proliferation
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	GIG1 CCN1
Also known as	Cyr61 Polyclonal Antibody
Other name	Anti-Cyr61 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	Cyr61
Short name	Anti-Cyr61 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	61 (polyclonal), ALEXA Fluor 594, angiogenic inducer, antibody to-cysteine-rich
Alternative technique	polyclonals
Identity	2654
Gene	CYR61
Long gene name	cysteine rich angiogenic inducer 61
Synonyms gene	IGFBP10
Synonyms gene name	61 , angiogenic inducer, cysteine-rich
Locus	1p22, 3
Discovery year	1998-03-02
GenBank acession	AF031385
Entrez gene record	3491
Pubmed identfication	9135077
RefSeq identity	NM_001554
Classification	CYR61/CTGF/NOV matricellular proteins
Havana BLAST/BLAT	OTTHUMG00000010577

Anti-Cyr61 (Polyclonal), ALEXA Fluor 594

Anti-Cyr61 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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