Filters

Anti-DAB2 (Polyclonal), ALEXA Fluor 594

Anti-DAB2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDAB2
SpecificityThis antibody reacts specifically with DAB2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human DAB2
Gene ID1601
Swiss ProtP98082
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Alternatively spliced transcript variants encoding different isoforms have been found for this gene, It is expressed in normal ovarian epithelial cells, Oct 2011], This protein binds to the SH3 domains of GRB2, [provided by RefSeq, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor, via its C-terminal proline-rich sequences, This gene encodes a mitogen-responsive phosphoprotein
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms DOC-2
Also known asDAB2 Polyclonal Antibody
Other nameAnti-DAB2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDAB2
Short nameAnti-DAB2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-DAB2 (polyclonal)
Alternative techniquepolyclonals
Identity 2662
Gene DAB2
Long gene name DAB2, clathrin adaptor protein
Synonyms gene name disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) disabled homolog 2, homolog 2 (Drosophila) , mitogen-responsive phosphoprotein, mitogen-responsive phosphoprotein (Drosophila) Dab
Locus 5p13, 1
Discovery year 1998-07-29
GenBank acession U53446
Entrez gene record 1601
Pubmed identfication 8660969 9620555
RefSeq identity NM_001343
Havana BLAST/BLAT OTTHUMG00000162043

Similar products

Subscribe to our Newsletter