Name : Anti-DAND5 (Polyclonal), FITC
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2559393931
| Type | Conjugated Primary Antibody |
| Conjugated with | FITC |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | DAND5 |
| Specificity | This antibody reacts specifically with DAND5 FITC |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Secreted, Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human DAND5 |
| Gene ID | 199699 |
| Swiss Prot | Q8N907 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Cystine knot-containing proteins play important roles during development, May antagonize NODAL and BMP4 signaling, organogenesis, tissue growth and differentiation (By similarity), Seems to play a role in the correct specification of the left-right axis |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 494nm/518nm |
| Synonyms | FLJ38607 CKTSF1B3 DANTE GREM3 CER2 DTE Coco |
| Also known as | DAND5 Polyclonal Antibody FITC |
| Other name | Anti-DAND5 Polyclonal FITC |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | Bioss Polyclonal Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, This Bioss Polyclonal Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS |
| Conjugation | Anti-FITC Antibody |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | DAND5 |
| Short name | Anti-DAND5 (Polyclonal) FITC |
| Technique | Fluorescein, Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | FITC |
| Alternative name | fluorecein, member 5 (polyclonal), antibody to-DAN domain family |
| Alternative technique | polyclonals |
| Alternative to gene target | DAND5 and IDBG-31601 and ENSG00000179284 and 199699, Dand5 and IDBG-174811 and ENSMUSG00000053226 and 23863, Extracellular, member 5, morphogen activity, this GO :0003140 and determination of left/right asymmetry in lateral mesoderm and biological process this GO :0003281 and ventricular septum development and biological process this GO :0003283 and atrial septum development and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0007368 and determination of left/right symmetry and biological process this GO :0016015 and morphogen activity and molecular function this GO :0017015 and regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0030514 and negative regulation of BMP signaling pathway and biological process this GO :0038101 and sequestering of nodal from receptor via nodal binding and biological process this GO :0061371 and determination of heart left/right asymmetry and biological process this GO :1900108 and negative regulation of nodal signaling pathway and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0016015: morphogen activity, this GO :0016015: morphogen activity, DAN domain family |
| Identity | 26780 |
| Gene | DAND5 |
| Long gene name | DAN domain BMP antagonist family member 5 |
| Synonyms gene name | BMP antagonist , DAN domain family member 5 |
| Locus | 19p13, 13 |
| Discovery year | 2005-01-04 |
| GenBank acession | AK095926 |
| Entrez gene record | 199699 |
| Pubmed identfication | 15254711 |
| RefSeq identity | NM_152654 |
| Classification | DAN family |
| Havana BLAST/BLAT | OTTHUMG00000180725 |