Name : anti-DC-SIGN Antibody [5D7]
Supplier : PROSCIENCE
Price :180
SKU : GEN3214989811
| Gene info | A DC-SIGN homologue (termed DC-SIGNR, DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR, DCs also amplify the amount of virus and extend the duration of viral infectivity, HIV-2 and SIV bind to DCs via DC-SIGN, ICAM-3 is the natural ligand for DC-SIGN, L-SIGN, Multiple strains of HIV-1, The expression of DC-SIGN was found in mucosal tissues including placenta, and DC-SIGN2) was identified recently, and rectum, small intestine, where DCs hand over HIV to CD4+ T lymphocytes, DC-SIGN Monoclonal Antibody: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes |
| Gene names | CLEC4L, DC-SIGN, DC-SIGN1, DC-SIGN Antibody [5D7] : CDSIGN |
| Antibodie's label | unlabelled serum |
| Purity | DC-SIGN Monoclonal Antibody is immunoaffinity chromotography purified IgG |
| Ab raised in | Mouse |
| Type | Monoclonal |
| Monoclonal | 5D7 |
| Antigen | A recombinant His-tagged protein fragment corresponding to the extracellular region of human DC-SIGN |
| Immuno application | Western Blot, immuno-histo-chemistry, ELISA |
| Antibody advice | DC-SIGN antibody can be used for detection of DC-SIGN in Western Blot at 1 - 2 mg/mL and in immunohistochemistry at 5 - 10 mg/mL |
| Suspention, pH, azide | 02% sodium azide, DC-SIGN Monoclonal Antibody is supplied in PBS containing 0 |
| Keep at | stable for one year, DC-SIGN monoclonal antibody can be stored at -20 grades C |
| Works with | Human |
| Omim nr | 46396012 |
| Ncbi nr | Q9NNX6 |
| Vial with antibody | in solution |
| Quantity per ml | 1 mg/mL |
| NCBI GENE nr | 30835 |
| GENE symbol | CD209 |
| Antigene name | CD209 molecule |
| Source | Homo sapiens |
| Protein nr | Q9NNX6 |
| Description | Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target | DC-SIGN [5D7] |
| Short name | anti-DC-SIGN Antibody [5D7] |
| Technique | antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name | antibody to-DC-SIGN (Antibody to) [5D7] |
| Alternative technique | antibodies |
| Identity | 1641 |
| Gene | CD209 |
| Long gene name | CD209 molecule |
| Synonyms gene name | CD209 antigen |
| Synonyms | DC-SIGN CDSIGN DC-SIGN1 CLEC4L |
| Locus | 19p13, 2 |
| Discovery year | 2000-07-19 |
| GenBank acession | M98457 |
| Entrez gene record | 30835 |
| Pubmed identfication | 1518869 |
| RefSeq identity | NM_021155 |
| Classification | CD molecules Scavenger receptors C-type lectin domain family |
| Havana BLAST/BLAT | OTTHUMG00000182530 |