Name : Anti-DCLREC1C/Artemis (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN9529029315
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | DCLREC1C/Artemis |
| Specificity | This antibody reacts specifically with DCLREC1C/Artemis |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Nucleus |
| Antigen Source | KLH conjugated synthetic peptide derived from human DCLREC1C/Artemis |
| Gene ID | 64421 |
| Swiss Prot | Q96SD1 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | (D), May also be required for the repair of complex DSBs induced by ionizing radiation, The latter activity is required specifically for the resolution of closed hairpins prior to the formation of the coding joint, These DSBs present two types of DNA end structures: hairpin sealed coding ends and phosphorylated blunt signal ends, These ends are independently repaired by the non homologous end joining (NHEJ) pathway to form coding and signal joints respectively, This protein exhibits single-strand specific 5'-3' exonuclease activity in isolation and acquires endonucleolytic activity on 5' and 3' hairpins and overhangs when in a complex with PRKDC, V(D)J recombination is initiated by the lymphoid specific RAG endonuclease complex, and J gene segments, the process by which exons encoding the antigen-binding domains of immunoglobulins and T-cell receptor proteins are assembled from individual V, which generates site specific DNA double strand breaks (DSBs), which require substantial end-processing prior to religation by NHEJ, Required for V(D)J recombination |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | A-SCID, ARTEMIS, ASCID, DCLRE1C, DCLREC1C, DNA cross-link repair 1C protein, Protein A-SCID, Protein artemis, RS-SCID, SNM1 homolog C, SNM1-like protein, SNM1C, hSNM1C, SCIDA |
| Also known as | DCLREC1C/Artemis Polyclonal Antibody |
| Other name | Anti-DCLREC1C/Artemis Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | DCLREC1C/Artemis |
| Short name | Anti-DCLREC1C/Artemis (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-DCLREC1C/Artemis (polyclonal) |
| Alternative technique | polyclonals |