Name : Anti-DENND2C (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN7974166454
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | DENND2C |
| Specificity | This antibody reacts specifically with DENND2C |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human DENND2C |
| Gene ID | 163259 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Gaucher disease and Usher syndrome, Other notable genes located on chromosome 1 include LMNA, Parkinsons, Stickler syndrome, The DENND2C protein is thought to target to actin filaments and control Rab9-dependent trafficking of mannose-6-phosphate receptor to lysosomes, The gene encoding DENND2C maps to human chromosome 1, a DENN domain, and a uDENN domain and exists as three isoforms as a result of alternative splicing, and the MUTYH gene, the largest human chromosome which spans about 260 million base pairs and makes up 8% of the human genome, which is associated with the rare aging disease Hutchinson-Gilford progeria, which is partially responsible for familial adenomatous polyposis, DENND2C is a 928 amino acid protein that contains a dDENN domain |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ37099 DKFZp686G0351 DKFZp779P1149 dJ1156J9, 1 , 1 RP5-1156J9 |
| Also known as | DENND2C Polyclonal Antibody |
| Other name | Anti-DENND2C Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | DENND2C |
| Short name | Anti-DENND2C (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-DENND2C (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 24748 |
| Gene | DENND2C |
| Long gene name | DENN domain containing 2C |
| Synonyms gene name | DENN/MADD domain containing 2C |
| Locus | 1p13, 2 |
| Discovery year | 2005-08-17 |
| Entrez gene record | 163259 |
| RefSeq identity | NM_198459 |
| Classification | DENN/MADD domain containing |
| Havana BLAST/BLAT | OTTHUMG00000011893 |