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Anti-DEPTOR (Polyclonal), ALEXA Fluor 594

Anti-DEPTOR (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDEPTOR
SpecificityThis antibody reacts specifically with DEPTOR
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human DEPTOR/DEPDC6
Gene ID64798
Swiss ProtQ8TB45
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Chromosome 8 consists of nearly 146 million base pairs, Containing two DEP domains and one PDZ (DHR) domain, DEPTOR interacts with FRAP via its PDZ domain, DEPTOR is encoded by a gene that maps to human chromosome 8q24, Pfeiffer syndrome, Schizophrenia, Trisomy 8, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8, also known as DEP, and undergoes post-translational phosphorylation, bipolar disorder, congenital hypothyroidism, encodes over 800 genes and is associated with a variety of diseases and malignancies, is a 409 amino acid protein that negatively regulates mTORC1 and mTORC2 pathways, 12, 6 or DEPDC6 (DEP domain-containing protein 6), DEPTOR (DEP domain containing MTOR-interacting protein)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms DEP, 6 FLJ12428
Also known asDEPTOR Polyclonal Antibody
Other nameAnti-DEPTOR Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDEPTOR
Short nameAnti-DEPTOR (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-DEP domain containing Mammalian target on rapamycin-interacting protein (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target BT, DEPTOR and IDBG-34051 and ENSG00000155792 and 64798, Deptor and IDBG-141160 and ENSMUSG00000022419 and 97998, multiple, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0032007 and negative regulation of TOR signaling and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0045792 and negative regulation of cell size and biological process this GO :2001236 and regulation of extrinsic apoptotic signaling pathway and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, 28648 and IDBG-645663 and ENSBTAG00000015341 and 617606, DEP domain containing MTOR-interacting protein
Identity 22953
Gene DEPTOR
Long gene name DEP domain containing MTOR interacting protein
Synonyms gene DEPDC6
Synonyms gene name DEP domain containing 6
Locus 8q24, 12
Discovery year 2004-02-23
Entrez gene record 64798
Pubmed identfication 19446321
RefSeq identity NM_022783
Classification PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000165052

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