Anti-DERLIN-1 (Polyclonal), ALEXA Fluor 594

Anti-DERLIN-1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	DERLIN-1
Specificity	This antibody reacts specifically with DERLIN-1
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human DERLIN-1
Gene ID	79139
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Derlin proteins are multi-pass membrane proteins localizing to the ER, Derlin-1, Derlins are involved in transferring misfolded proteins from the ER to the cytosol, Derlins may also be important for cell proliferation, In the case of cytomegalovirus infection, also designated Derlins or DERtrins, are crucial for the degradation of misfolded endoplasmic reticulum (ER) luminal proteins, as opposed to Derlins-2 and -3, is involved in the export of MHC class I heavy chains from the ER via its interaction with the viral protein US11, where the misfolded proteins are destroyed in an ubiquitin-dependent manner by the proteasome, Degradation in endoplasmic reticulum proteins
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	MGC3067 PRO2577 FLJ13784 DER1 DER-1 derlin-1
Also known as	DERLIN-1 Polyclonal Antibody
Other name	Anti-DERLIN-1 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	DERLIN-1
Short name	Anti-DERLIN-1 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-DERLIN-1 (polyclonal)
Alternative technique	polyclonals
Identity	28454
Gene	DERL1
Long gene name	derlin 1
Synonyms gene name	Der1-like domain family, member 1
Locus	8q24, 13
Discovery year	2004-11-02
GenBank acession	BC002457
Entrez gene record	79139
Pubmed identfication	12975309 15215855
RefSeq identity	NM_024295
Classification	Rhomboid family
Havana BLAST/BLAT	OTTHUMG00000165080

Anti-DERLIN-1 (Polyclonal), ALEXA Fluor 594

Anti-DERLIN-1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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