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Anti-DERP6 (Polyclonal), ALEXA Fluor 594

Anti-DERP6 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDERP6
SpecificityThis antibody reacts specifically with DERP6
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human DERP6/C17orf81
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information BRCA1 is directly involved in DNA repair, DERP6 is thought to be involved in p53-mediated transcriptional regulation, Expressed ubiquitously with highest expression in liver, Like p53, Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome, The gene encoding DERP6 maps to human chromosome 17, Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death, Two key tumor suppressor genes are associated with chromosome 17, brain and skeletal muscle, colon, heart, is a 316 amino acid protein that localizes to the cytoplasm and exists as multiple alternatively spliced isoforms, namely, p53 and BRCA1, prostate gland and fallopian tubes, testis, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, which comprises over 2, 200 genes, 5% of the human genome and encodes over 1, DERP6
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms DERP6
Also known asDERP6 Polyclonal Antibody
Other nameAnti-DERP6 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDERP6
Short nameAnti-DERP6 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-DERP6 (polyclonal)
Alternative techniquepolyclonals
Identity 30617
Gene ELP5
Long gene name elongator acetyltransferase complex subunit 5
Synonyms gene C17orf81
Synonyms gene name chromosome 17 open reading frame 81
Synonyms name dermal papilla derived protein 6 S-phase 2 protein
Locus 17p13, 1
Discovery year 2006-02-13
GenBank acession BC002762
Entrez gene record 23587
Pubmed identfication 22854966
RefSeq identity NM_015362
Classification Elongator acetyltransferase complex
Havana BLAST/BLAT OTTHUMG00000177974

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