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Anti-Desmoglein 4 (Polyclonal), ALEXA Fluor 594

Anti-Desmoglein 4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDesmoglein 4
SpecificityThis antibody reacts specifically with Desmoglein 4
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human Desmoglein 4
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information 37% with human desmoglein 2 and 50% with human desmoglein 3, A type I membrane protein of the cadherin protein family, Desmoglein 4 (dsg4) shares 41% identity with human desmoglein 1, In the hair follicle, The human DSG4 gene is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 and DSG3, dsg4 is an important mediator of keratinocyte cell adhesion and coordinates the transition from proliferation to differentiation, dsg4 is expressed in salivary gland, hair follicle, prostate and skin, suprabasal epidermis, testis, Desmoglein proteins are cadherin-type cell adhesion molecules
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CDHF13 LAH
Also known asDesmoglein 4 Polyclonal Antibody
Other nameAnti-Desmoglein 4 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDesmoglein 4
Short nameAnti-Desmoglein 4 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Desmoglein 4 (polyclonal)
Alternative techniquepolyclonals
Identity 21307
Gene DSG4
Long gene name desmoglein 4
Locus 18q12, 1
Discovery year 2003-06-04
GenBank acession AY177664 AY168788
Entrez gene record 147409
Pubmed identfication 12648213
RefSeq identity NM_177986
Classification Desmosomal cadherins
Havana BLAST/BLAT OTTHUMG00000131979

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