Name : Anti-DHRS2 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6571031818
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | DHRS2 |
| Specificity | This antibody reacts specifically with DHRS2 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human DHRS2 |
| Gene ID | 10202 |
| Swiss Prot | Q13268 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | 2, Attenuates MDM2-mediated p53/TP53 degradation, No reductase activity is displayed in vitro with steroids, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21, retinoids and sugars as substrates, 2-propanedione as substrates, 3-Heptanedione and 1-Phenyl-1, 4-Hexanedione, Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3 |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | HEP27 SDR25C1 |
| Also known as | DHRS2 Polyclonal Antibody |
| Other name | Anti-DHRS2 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | DHRS2 |
| Short name | Anti-DHRS2 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-dehydrogenase/reductase (SDR family) member 2 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | DHRS2 and IDBG-3407 and ENSG00000100867 and 10202, Dhrs2 and IDBG-163262 and ENSMUSG00000022209 and 71412, HEP27 and SDR25C1, nuclei, oxidoreductase activity, this GO :0004090 and carbonyl reductase (NADPH) activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0005635 and nuclear envelope and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0008152 and metabolic process and biological process this GO :0008207 and C21-steroid hormone metabolic process and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009636 and response to toxic substance and biological process this GO :0016491 and oxidoreductase activity and molecular function this GO :0034599 and cellular response to oxidative stress and biological process this GO :0043011 and myeloid dendritic cell differentiation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004090: carbonyl reductase (NADPH) activity, this GO :0004090: carbonyl reductase (NADPH) activity and also this GO :0016491: oxidoreductase activity, this GO :0016491: oxidoreductase activity, dehydrogenase/reductase (SDR family) member 2 |
| Identity | 18349 |
| Gene | DHRS2 |
| Long gene name | dehydrogenase/reductase 2 |
| Synonyms gene name | dehydrogenase/reductase (SDR family) member 2 |
| Synonyms name | member 1 , short chain dehydrogenase/reductase family 25C |
| Locus | 14q11, 2 |
| Discovery year | 2002-04-26 |
| Entrez gene record | 10202 |
| Pubmed identfication | 7556196 11944995 16685466 19027726 |
| RefSeq identity | NM_182908 |
| Classification | Short chain dehydrogenase/reductase superfamily |
| Havana BLAST/BLAT | OTTHUMG00000028771 |