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Anti-DIRAS1 (Polyclonal), ALEXA Fluor 594

Anti-DIRAS1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDIRAS1
SpecificityThis antibody reacts specifically with DIRAS1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human DIRAS1
Gene ID148252
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information It is highly expressed in heart and brain, N-Ras and K-Ras4A and K-Ras4B (the two K-Ras proteins arise from alternative gene splicing), Ras and ras-related proteins are often deregulated in cancers, Ras proteins function as binary molecular switches that control intracellular signaling networks, Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, and cell migration, and decreased apoptosis, apoptosis, cell adhesion, designated H-Ras, differentiation, leading to increased invasion and metastasis, proliferation, DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form, The three human RAS genes encode highly related 188 to 189 amino acid proteins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Di-Ras1 GBTS1 RIG
Also known asDIRAS1 Polyclonal Antibody
Other nameAnti-DIRAS1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDIRAS1
Short nameAnti-DIRAS1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-DIRAS1 (polyclonal)
Alternative techniquepolyclonals
Identity 19127
Gene DIRAS1
Long gene name DIRAS family GTPase 1
Synonyms gene name DIRAS family, GTP-binding RAS-like 1
Locus 19p13, 3
Discovery year 2003-02-07
GenBank acession BC030660
Entrez gene record 148252
Pubmed identfication 12107278
Classification RAS type GTPase family
Havana BLAST/BLAT OTTHUMG00000180439

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