Anti-DKK1 (Polyclonal), ALEXA Fluor 594

Anti-DKK1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	DKK1
Specificity	This antibody reacts specifically with DKK1
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Secreted
Antigen Source	KLH conjugated synthetic peptide derived from human DKK1
Gene ID	22943
Swiss Prot	O94907
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Dog, Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	DKKs play an important role in vertebrate development, Dkks are implicated in bone formation and bone disease, In the adult, cancer and Alzheimer disease, limb development, somitogenesis and eye formation, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	SK DKK-1
Also known as	DKK1 Polyclonal Antibody
Other name	Anti-DKK1 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	DKK1
Short name	Anti-DKK1 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-DKK1 (polyclonal)
Alternative technique	polyclonals
Identity	2891
Gene	DKK1
Long gene name	dickkopf WNT signaling pathway inhibitor 1
Synonyms gene name	dickkopf (Xenopus laevis) homolog 1 dickkopf 1 homolog (Xenopus laevis)
Locus	10q21, 1
Discovery year	2000-09-01
Entrez gene record	22943
Havana BLAST/BLAT	OTTHUMG00000018247

Anti-DKK1 (Polyclonal), ALEXA Fluor 594

Anti-DKK1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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