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Anti-DLC1 (Polyclonal), ALEXA Fluor 594

Anti-DLC1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDLC1
SpecificityThis antibody reacts specifically with DLC1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Mitochondrion, Nucleus, Cytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human DLC1
Gene ID8655
Swiss ProtP63167
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Binds and inhibits the catalytic activity of neuronal nitric oxide synthase, Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules, May play a role in changing or maintaining the spatial distribution of cytoskeletal structures, Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1, Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules, Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity, Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms DLC1 CFAP81
Also known asDLC1 Polyclonal Antibody
Other nameAnti-DLC1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDLC1
Short nameAnti-DLC1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-deleted in liver cancer 1 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target ARHGAP7 and HP and p122-RhoGAP and STARD12, BT, DLC1 and IDBG-7954 and ENSG00000164741 and 10395, Dlc1 and IDBG-149173 and ENSMUSG00000031523 and 50768, SH2 domain binding, nuclei, this GO :0001843 and neural tube closure and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0005100 and Rho GTPase activator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005901 and caveola and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008289 and lipid binding and molecular function this GO :0008360 and regulation of cell shape and biological process this GO :0021575 and hindbrain morphogenesis and biological process this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030336 and negative regulation of cell migration and biological process this GO :0030900 and forebrain development and biological process this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0032956 and regulation of actin cytoskeleton organization and biological process this GO :0035024 and negative regulation of Rho protein signal transduction and biological process this GO :0035307 and positive regulation of protein dephosphorylation and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0048041 and focal adhesion assembly and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0051497 and negative regulation of stress fiber assembly and biological process this GO :1900119 and positive regulation of execution phase of apoptosis and biological process, this GO :0005100: Rho GTPase activator activity, this GO :0005100: Rho GTPase activator activity and also this GO :0005515: protein binding and also this GO :0008289: lipid binding and also this GO :0042169: SH2 domain binding, this GO :0005515: protein binding, this GO :0008289: lipid binding, this GO :0042169: SH2 domain binding, 24236 and IDBG-628726 and ENSBTAG00000015541 and 511433, deleted in liver cancer 1
Identity 2899
Gene DLEC1
Long gene name deleted in lung and esophageal cancer 1
Synonyms name cilia and flagella associated protein 81
Locus 3p22, 2
Discovery year 1999-05-07
GenBank acession AB020522
Entrez gene record 9940
Pubmed identfication 10213508
RefSeq identity NM_007337
Havana BLAST/BLAT OTTHUMG00000131085

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