Name : Anti-DLG5 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3066015753
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | DLG5 |
| Specificity | This antibody reacts specifically with DLG5 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human DLG5 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | CARD8-12 and CARD14, DLG5, DLG5, DLG5 which can interact with MPP1 and CTNNB1, GKAP (GK-associated protein), It also plays an important part in transmitting extracellular signals to the cytoskeleton and the membrane, MAGUK family members include the postsynaptic proteins PSD-93, NE-dlg (SAP 120), PSD-95 (SAP 90), Pals1, Several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product belong to the MAGUK family, a cell-cell junction peripheral membrane protein, densin-180, dlg-1 (SAP 97), is primarily expressed in prostate and placenta, p55, plays an important role in maintaining the structure of epithelial cell plasma membranes, the tight junction associated proteins ZO-1-3 and the caspase-associated recruitment domain (CARD) proteins CARD6, Membrane-associated guanylate kinase (MAGUK) family members function as molecular scaffolds for the assembly of multiprotein complexes localizing to the plasma membrane |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | P-dlg KIAA0583 |
| Also known as | DLG5 Polyclonal Antibody |
| Other name | Anti-DLG5 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | DLG5 |
| Short name | Anti-DLG5 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, large homolog 5 (Drosophila) (polyclonal), antibody to-discs |
| Alternative technique | polyclonals |
| Alternative to gene target | Cell surfaces, DLG5 and IDBG-630788 and ENSBTAG00000013187 and 535699, DLG5 and IDBG-79872 and ENSG00000151208 and 9231, Dlg5 and IDBG-138094 and ENSMUSG00000021782 and 71228, LP-DLG and P-DLG5 and PDLG, large homolog 5 (Drosophila), receptor signaling complex scaffold activity, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005913 and cell-cell adherens junction and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0007165 and signal transduction and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0008092 and cytoskeletal protein binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0030159 and receptor signaling complex scaffold activity and molecular function this GO :0030859 and polarized epithelial cell differentiation and biological process this GO :0030901 and midbrain development and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0045176 and apical protein localization and biological process this GO :0045186 and zonula adherens assembly and biological process this GO :0045197 and establishment or maintenance of epithelial cell apical/basal polarity and biological process this GO :0060441 and epithelial tube branching involved in lung morphogenesis and biological process this GO :0071896 and protein localization to adherens junction and biological process this GO :0072205 and metanephric collecting duct development and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008013: beta-catenin binding and also this GO :0008092: cytoskeletal protein binding and also this GO :0030159: receptor signaling complex scaffold activity, this GO :0008013: beta-catenin binding, this GO :0008092: cytoskeletal protein binding, this GO :0030159: receptor signaling complex scaffold activity, discs |
| Identity | 2904 |
| Gene | DLG5 |
| Long gene name | discs large MAGUK scaffold protein 5 |
| Synonyms gene name | discs, large homolog 5 (Drosophila) discs large homolog 5 |
| Locus | 10q22, 3 |
| Discovery year | 1999-02-23 |
| GenBank acession | U61843 |
| Entrez gene record | 9231 |
| Pubmed identfication | 9738934 |
| RefSeq identity | NM_004747 |
| Classification | Membrane associated guanylate kinases PDZ domain containing |
| Havana BLAST/BLAT | OTTHUMG00000018548 |