Name : Anti-DNA polymerase delta (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2733314080
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | DNA polymerase delta |
| Specificity | This antibody reacts specifically with DNA polymerase delta |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human DNA polymerase delta |
| Gene ID | 5425 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Î, &, DNA pol Î, DNA pol Î, DNA pol &, DNA pol &, In DNA replication, The nuclear-encoded DNA pol &, These exonucleases include the family of DNA polymerases (3), all of which are necessary for genomic stability, and DNA pol e are multisubunit enzymes, and e are involved in DNA replication and repair (4), and p50 (5), consisting of two subunits p125, is a DNA polymerase-helicase that binds ATP and is involved in the repair of interstrand crosslinks (8), is the only DNA polymerase required for the replication of the mitochondrial DNA (6), is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis (7), recombination and repair, require the presence of exonucleases (1), these enzymes are involved in the processing of Okazaki fragments, they function to excise damaged DNA fragments and correct recombinational mismatches (2), whereas in DNA repair, which interacts with the sliding DNA clamp protein PCNA, with DNA pol &, #339, #8706, #8706, #8706, ©, ±, ², DNA replication, copy |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | p12 POLDS |
| Also known as | DNA polymerase delta Polyclonal Antibody |
| Other name | Anti-DNA polymerase delta Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | DNA polymerase delta |
| Short name | Anti-DNA polymerase delta (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Desoxyribonucleic acid polymerizing enzyme delta (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 14106 |
| Gene | POLD4 |
| Long gene name | DNA polymerase delta 4, accessory subunit |
| Synonyms gene name | accessory subunit , accessory subunit polymerase (DNA) delta 4, delta 4, polymerase (DNA-directed) |
| Synonyms name | DNA polymerase delta smallest subunit p12 |
| Locus | 11q13, 2 |
| Discovery year | 2000-12-04 |
| GenBank acession | AF179890 |
| Entrez gene record | 57804 |
| Pubmed identfication | 10751307 |
| RefSeq identity | NM_021173 |
| Classification | DNA polymerases |
| Havana BLAST/BLAT | OTTHUMG00000167135 |