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Anti-DNase I (Polyclonal), ALEXA Fluor 594

Anti-DNase I (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDNase I
SpecificityThis antibody reacts specifically with DNase I
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human DNase I
Gene ID1773
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis, A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, DNase I attacks each strand of DNA independently and the cleavage sites are random, DNase I is a Ca2+ and Mg2+ dependant endonuclease, DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides, DNase I is synthesized in the pancreas and stored in zymogen granules, In the form of a bovine pancreatic enzyme preparation, In the presence of Mg ion, It has been used to reduce the viscosity of cystic fibrosis sputum, The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides, and it was the first DNase for which a specific protein inhibitor was characterized, cells susceptible to apoptosis, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognized as specific for DNA, it was the first DNase to be crystallized, 2 kb long with 9 exons separated by 8 introns, Deoxyribonuclease I gene is approximately 3
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms DNAS1L3 LSD
Also known asDNase I Polyclonal Antibody
Other nameAnti-DNase I Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDNase I
Short nameAnti-DNase I (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-DNase I (polyclonal)
Alternative techniquepolyclonals
Identity 2959
Gene DNASE1L3
Long gene name deoxyribonuclease 1 like 3
Synonyms gene name deoxyribonuclease I like 3
Synonyms name DNase gamma
Locus 3p14, 3
Discovery year 1997-05-15
GenBank acession AF047354
Entrez gene record 1776
Pubmed identfication 9205125 9714828 14646506
RefSeq identity NM_004944
Havana BLAST/BLAT OTTHUMG00000159153

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