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Anti-Dnmt1 (Polyclonal), ALEXA Fluor 594

Anti-Dnmt1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDnmt1
SpecificityDnmt1, This antibody will not recongize isoform 3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human Dnmt1
Gene ID1786
Swiss ProtP26358
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication, DNA methylation is coordinated with methylation of histones, In association with DNMT3B and via the recruitment of CTCFL/BORIS, It is responsible for maintaining methylation patterns established in development, Mediates transcriptional repression by direct binding to HDAC2, Preferentially methylates hemimethylated DNA, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9, that is essential for epigenetic inheritance, Methylates CpG residues
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MCMT CXXC9 DNMT1
Also known asDnmt1 Polyclonal Antibody
Other nameAnti-Dnmt1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDnmt1
Short nameAnti-Dnmt1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Dnmt1 (polyclonal)
Alternative techniquepolyclonals
Identity 2975
Gene DNMT
Long gene name DNA methyltransferase 1
Synonyms gene name DNA (cytosine-5-)-methyltransferase 1
Locus 19p13, 2
Discovery year 1991-06-04
GenBank acession X63692
Entrez gene record 1786
Pubmed identfication 1594447
RefSeq identity NM_001379
Classification Zinc fingers CXXC-type
Havana BLAST/BLAT OTTHUMG00000180397
Locus Specific Databases LRG_362

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