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Anti-DOCK5 (Polyclonal), ALEXA Fluor 594

Anti-DOCK5 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDOCK5
SpecificityThis antibody reacts specifically with DOCK5
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human DOCK5
Gene ID80005
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information DOCK 5 contains one DHR-1 (CZH-1) domain, Due to siRNA knockdown studies, In mice, The DHR-2 domain is a putative GEF activity mediator, There are two isoforms of DOCK 5 that exist as a result of alternative splicing events, This cytoplasmic peripheral membrane protein activates Rac 1 and Rac 2 small GTPases, it is suspected that DOCK 5 may also be an important mediator of CrkII/CrkL regulation of Caco-2 migration and spreading on COL4, one DHR-2 (CZH-2) domain and one SH3 domain, resulting in rupture of lens cataract (RLC), spontaneous mutation of the gene encoding DOCK 5 leads to deletion of the DHR-1 domain, which exchanges bound GDP for free GTP, which functions to bind phospholipids and assists in protein-protein interactions, while presumably acting as a guanine nucleotide exchange factor (GEF), 870 amino acid protein belonging to the DOCK family of cytokinesis-regulating proteins, DOCK 5 is a 1
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ21034
Also known asDOCK5 Polyclonal Antibody
Other nameAnti-DOCK5 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDOCK5
Short nameAnti-DOCK5 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-dedicator on cytokinesis 5 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target Cytoplasm, DOCK5 and IDBG-12661 and ENSG00000147459 and 80005, DOCK5 and IDBG-635373 and ENSBTAG00000015513 and 505572, Dock5 and IDBG-176271 and ENSMUSG00000044447 and 68813, protein binding, this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0043547 and positive regulation of GTPase activity and biological process, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005488: binding and also this GO :0005515: protein binding, this GO :0005488: binding, this GO :0005515: protein binding, dedicator of cytokinesis 5
Identity 23476
Gene DOCK5
Long gene name dedicator of cytokinesis 5
Locus 8p21, 2
Discovery year 2003-11-19
Entrez gene record 80005
Pubmed identfication 12432077
RefSeq identity NM_024940
Havana BLAST/BLAT OTTHUMG00000131991

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