Name : Anti-DOK6 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5451731637
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | DOK6 |
| Specificity | This antibody reacts specifically with DOK6 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human DOK6 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK), Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1, Dok-5 transcript is abundant in muscle and increases during T cell activation, Dok-6 is highly expressed in the developing central nervous system, It associates with Ret to transduce Ret-mediated processes such as axonal projection, and may constitute a subfamily of the DOK genes, which contain multiple tyrosine residues and putative SH2 binding sites, &euro, &euro, &oelig, The downstream of kinase family (Dok-1-7) are members of a class of â, dockingâ, proteins that include the tyrosine kinase substrates IRS-1 and Cas |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | MGC20785 HsT3226 |
| Also known as | DOK6 Polyclonal Antibody |
| Other name | Anti-DOK6 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | DOK6 |
| Short name | Anti-DOK6 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-DOK6 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 28301 |
| Gene | DOK6 |
| Long gene name | docking protein 6 |
| Synonyms gene | DOK5L |
| Synonyms gene name | docking protein 5-like |
| Locus | 18q22, 2 |
| Discovery year | 2004-05-05 |
| GenBank acession | AK057795 |
| Entrez gene record | 220164 |
| Pubmed identfication | 15286081 |
| RefSeq identity | NM_152721 |
| Classification | Pleckstrin homology domain containing |
| Havana BLAST/BLAT | OTTHUMG00000178688 |