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Anti-DOK6 (Polyclonal), ALEXA Fluor 594

Anti-DOK6 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDOK6
SpecificityThis antibody reacts specifically with DOK6
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human DOK6
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK), Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1, Dok-5 transcript is abundant in muscle and increases during T cell activation, Dok-6 is highly expressed in the developing central nervous system, It associates with Ret to transduce Ret-mediated processes such as axonal projection, and may constitute a subfamily of the DOK genes, which contain multiple tyrosine residues and putative SH2 binding sites, &euro, &euro, &oelig, The downstream of kinase family (Dok-1-7) are members of a class of â, dockingâ,  proteins that include the tyrosine kinase substrates IRS-1 and Cas
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MGC20785 HsT3226
Also known asDOK6 Polyclonal Antibody
Other nameAnti-DOK6 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDOK6
Short nameAnti-DOK6 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-DOK6 (polyclonal)
Alternative techniquepolyclonals
Identity 28301
Gene DOK6
Long gene name docking protein 6
Synonyms gene DOK5L
Synonyms gene name docking protein 5-like
Locus 18q22, 2
Discovery year 2004-05-05
GenBank acession AK057795
Entrez gene record 220164
Pubmed identfication 15286081
RefSeq identity NM_152721
Classification Pleckstrin homology domain containing
Havana BLAST/BLAT OTTHUMG00000178688

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