Filters

Anti-DTX2 (Polyclonal), ALEXA Fluor 594

Anti-DTX2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDTX2
SpecificityThis antibody reacts specifically with DTX2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human DTX2
Gene ID113878
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information DTX2 also functions as an ubiquitin ligase protein in vitro, DTX2 is a regulator of Notch signaling, It contains one RING-type zinc finger and two WWE domains, It probably acts both as a positive and negative regulator of Notch, The WWE domains are thought to mediate some protein-protein interaction, There are two named isoforms, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations, and are frequently found in ubiquitin ligases, depending on the developmental and cell context, mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity, DTX2 belongs to the Deltex family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms RNF58 KIAA1528
Also known asDTX2 Polyclonal Antibody
Other nameAnti-DTX2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDTX2
Short nameAnti-DTX2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-DTX2 (polyclonal)
Alternative techniquepolyclonals
Identity 15973
Gene DTX2
Long gene name deltex E3 ubiquitin ligase 2
Synonyms gene name E3 ubiquitin ligase , deltex (Drosophila) homolog 2 deltex homolog 2 (Drosophila) deltex 2
Locus 7q11, 23
Discovery year 2001-08-13
Entrez gene record 113878
Pubmed identfication 12670957
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000162594

Subscribe to our Newsletter