Name : Anti-DTX2 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3020457845
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | DTX2 |
| Specificity | This antibody reacts specifically with DTX2 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human DTX2 |
| Gene ID | 113878 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | DTX2 also functions as an ubiquitin ligase protein in vitro, DTX2 is a regulator of Notch signaling, It contains one RING-type zinc finger and two WWE domains, It probably acts both as a positive and negative regulator of Notch, The WWE domains are thought to mediate some protein-protein interaction, There are two named isoforms, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations, and are frequently found in ubiquitin ligases, depending on the developmental and cell context, mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity, DTX2 belongs to the Deltex family |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | RNF58 KIAA1528 |
| Also known as | DTX2 Polyclonal Antibody |
| Other name | Anti-DTX2 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | DTX2 |
| Short name | Anti-DTX2 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-DTX2 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 15973 |
| Gene | DTX2 |
| Long gene name | deltex E3 ubiquitin ligase 2 |
| Synonyms gene name | E3 ubiquitin ligase , deltex (Drosophila) homolog 2 deltex homolog 2 (Drosophila) deltex 2 |
| Locus | 7q11, 23 |
| Discovery year | 2001-08-13 |
| Entrez gene record | 113878 |
| Pubmed identfication | 12670957 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000162594 |