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Anti-DUSP3 (Polyclonal), ALEXA Fluor 594

Anti-DUSP3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDUSP3
SpecificityThis antibody reacts specifically with DUSP3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human DUSP3
Gene ID1845
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Although DUSP3 is expressed in both breast and ovarian tissues, Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, SAPK/JNK, These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues, They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer, and different modes of inducibility of their expression by extracellular stimuli, different tissue distribution and subcellular localization, leading to the conclusion that this gene is not BRCA1, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, p38), which are associated with cellular proliferation and differentiation, The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asDUSP3 Polyclonal Antibody
Other nameAnti-DUSP3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDUSP3
Short nameAnti-DUSP3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-dual specificity phosphatase 3 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target DUSP3 and IDBG-52945 and ENSG00000108861 and 1845, DUSP3 and IDBG-640759 and ENSBTAG00000003966 and 615432, Dusp3 and IDBG-212400 and ENSMUSG00000003518 and 72349, MAP kinase phosphatase activity, VHR, nuclei, this GO :0000188 and inactivation of MAPK activity and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001772 and immunological synapse and cellular component this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004721 and phosphoprotein phosphatase activity and molecular function this GO :0004725 and protein tyrosine phosphatase activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006470 and protein dephosphorylation and biological process this GO :0008138 and protein tyrosine/serine/threonine phosphatase activity and molecular function this GO :0016311 and dephosphorylation and biological process this GO :0016791 and phosphatase activity and molecular function this GO :0033549 and MAP kinase phosphatase activity and molecular function this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035335 and peptidyl-tyrosine dephosphorylation and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0045087 and innate immune response and biological process this GO :0045931 and positive regulation of mitotic cell cycle and biological process this GO :0046329 and negative regulation of JNK cascade and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0050860 and negative regulation of T cell receptor signaling pathway and biological process this GO :0050868 and negative regulation of T cell activation and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070373 and negative regulation of ERK1 and ERK2 cascade and biological process, this GO :0004721: phosphoprotein phosphatase activity, this GO :0004721: phosphoprotein phosphatase activity and also this GO :0004725: protein tyrosine phosphatase activity and also this GO :0008138: protein tyrosine/serine/threonine phosphatase activity and also this GO :0016791: phosphatase activity and also this GO :0033549: MAP kinase phosphatase activity, this GO :0004725: protein tyrosine phosphatase activity, this GO :0008138: protein tyrosine/serine/threonine phosphatase activity, this GO :0016791: phosphatase activity, this GO :0033549: MAP kinase phosphatase activity, dual specificity phosphatase 3
Identity 3069
Gene DUSP3
Long gene name dual specificity phosphatase 3
Synonyms gene VHR
Synonyms gene name vaccinia virus phosphatase VH1-related
Locus 17q21, 31
Discovery year 1994-05-19
GenBank acession BC035701
Entrez gene record 1845
Pubmed identfication 7829094
RefSeq identity NM_004090
Classification Atypical dual specificity phosphatases
Havana BLAST/BLAT OTTHUMG00000180889

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