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Anti-DUSP5 (Polyclonal), Biotin

Anti-DUSP5 (Polyclonal), Biotin size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated withBiotin
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDUSP5
SpecificityThis antibody reacts specifically with DUSP5 Biotin
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human DUSP5
Gene ID1847
Swiss ProtN/A
ApplicationsWB
Applications with corresponding dilutionsWB(1:100-1000)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information DSP gene expression is induced by a host of growth factors and/or cellular stresses, DUSP1, DUSP5, DUSP5 is a nuclear phosphoprotein that displays phosphatase activity toward several different substrates, DUSP8, It shows the highest relative activity toward ERK1, MKP-2, MKP-3, MKP-4, MKP-5, MKP-6, MKP-7, MKP-X, PAC1, PIR1 and SKRP1, PYST2, SAPK/JNK and p38, The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, VHY, hVH-3 (B23), hVH-5, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases, Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emissionN/A
Synonyms HVH3
Also known asDUSP5 Polyclonal Antibody Biotin
Other nameAnti-DUSP5 Polyclonal Biotin
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, Biotin conjugates can be detected by horseradish peroxidase
ConjugationBiotinylated
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDUSP5
Short nameAnti-DUSP5 (Polyclonal)
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelBiotin
Alternative name biotinilated, antibody to-DUSP5 (polyclonal)
Alternative techniquepolyclonals
Identity 3071
Gene DUSP5
Long gene name dual specificity phosphatase 5
Locus 10q25, 2
Discovery year 1994-12-14
GenBank acession U16996
Entrez gene record 1847
Pubmed identfication 7806236
RefSeq identity NM_004419
Classification MAP kinase phosphatases
Havana BLAST/BLAT OTTHUMG00000019040

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