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Anti-DVL1 (Polyclonal), ALEXA Fluor 594

Anti-DVL1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDVL1
SpecificityThis antibody reacts specifically with DVL1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Cell membrane, Cytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human DVL1
Gene ID1855
Swiss ProtO14640
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ), Plays a role both in canonical and non-canonical Wnt signaling, Plays a role in the signal transduction pathways mediated by multiple Wnt genes, Required for LEF1 activation upon WNT1 and WNT3A signaling, Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asDVL1 Polyclonal Antibody
Other nameAnti-DVL1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDVL1
Short nameAnti-DVL1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-DVL1 (polyclonal)
Alternative techniquepolyclonals
Identity 3084
Gene DVL1
Long gene name dishevelled segment polarity protein 1
Synonyms gene name dishevelled 1 (homologous to Drosophila dsh) dishevelled, dsh homolog 1 (Drosophila)
Locus 1p36, 33
Discovery year 1996-03-12
GenBank acession AF006011
Entrez gene record 1855
Pubmed identfication 8817329
RefSeq identity NM_004421
Classification Dishevelled segment polarity proteins PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000003069

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