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Anti-DVL2 (Thr224) (Polyclonal), ALEXA Fluor 594

Anti-DVL2 (Thr224) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDVL2 Thr224
SpecificityThis antibody will recognize DVL3 when phosphorylated at Thr205DVL2 (Thr224)
ModificationPhosphorylation
Modification siteThr224
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human DVL2 around the phosphorylation site of Thr224
Gene ID1856
Swiss ProtO14641
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Plays a role both in canonical and non-canonical Wnt signaling, Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity), Promotes internalization and degradation of frizzled proteins upon Wnt signaling, Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asDVL2 (Thr224) Polyclonal Antibody
Other nameAnti-DVL2 (Thr224) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDVL2 (Thr224)
Short nameAnti-DVL2 (Thr224) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-DVL2 (Thr224) (polyclonal)
Alternative techniquepolyclonals
Identity 3086
Gene DVL2
Long gene name dishevelled segment polarity protein 2
Synonyms gene name dishevelled 2 (homologous to Drosophila dsh) dishevelled, dsh homolog 2 (Drosophila)
Locus 17p13, 1
Discovery year 1996-03-12
GenBank acession BC014844
Entrez gene record 1856
Pubmed identfication 8662242
RefSeq identity NM_004422
Classification Dishevelled segment polarity proteins PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000102155

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